Interactions With Benzodiazepines and Other CNS Depressants Inform patients and caregivers that potentially deadly additive effects could occur if acetaminophen and codeine phosphate tablets are used with benzodiazepines or other CNS depressants, which include alcohol, and never to employ these drugs concomitantly Until supervised by a healthcare company (see WARNINGS https://codeine.store/product/promethazine-hydrochloride/